Tuberculosis: A Cunning Disease Presenting with Endopericarditis- Associated Bilateral Uveitis

Tuberculosis: A Cunning Disease Presenting with Endopericarditis- Associated Bilateral Uveitis

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Mycobacterium tuberculosis can spread through the entire body but rarely involves the eye.We report a patient with endophthalmitis in one eye and simultaneous retinal vasculitis in the fellow eye.Systemic work-up suggested infective endopericarditis.Polymerase chain reaction nyx 22 brush analyses of the vitreous and pericardial fluid were positive for M.

tuberculosis.We initiated a four-drug antituberculous treatment regimen (isoniazid, ethambutol, pyrazinamide, and rifampin).After two weeks, we discontinued all the medications due to drug-induced hepatitis.We restarted isoniazid and rifampin, but hepatitis recurred.

Finally, we chose isoniazid/ethambutol combination for 18 months, and also administered short-term systemic corticosteroid.His vision improved considerably with no recurrence of hepatitis or tuberculosis for 3 years after completion of treatment.Ocular tuberculosis can masquerade as other causes of intraocular inflammation, and a medical team consisting of an ophthalmologist and an infectious disease specialist might be needed for sheepshead bay boats the diagnosis and management.